Thrombocytopenia is low blood platelet count.
leukemia or an immune system problem

Symptoms of Thrombocytopenia are as….

◆Petechiae on leg and abdomen.
◆Easy or excessive bruising (purpura).
◆Superficial bleeding into the skin.
◆Prolonged bleeding from cuts.
◆Bleeding from your gums or nose.
◆Blood in urine or stools.

Also, Unusually heavy :-
◆Heavy Menstrual flows
◆Enlarged spleen

Causes of Thrombocytopenia :-

◆Life span of platelet :- It is about 10 days, your body normally renews your platelet supply continually by producing new platelets in your bone marrow.

◆Thrombocytopenia rarely is inherited or it can be caused by a number of medications or conditions.

◆Whatever the cause, circulating platelets are reduced by one or more of the following processes like :-

1.Trapping of platelets in the spleen.

2.Decreased platelet production.

3.Increased destruction of platelets.

1. Trapped platelets –

=> The spleen is a small organ about the size of your fist situated just below your rib cage on the left side of your abdomen.

=> Normally, your spleen works to fight infection and filter unwanted material from your blood.

=> An enlarged spleen — which can be caused by a number of disorders can harbor too many platelets, which decreases the number of platelets in circulation.

2.Decreased production of platelets :-

=> Platelets are produced in your bone marrow.

=> Factors that can decrease platelet production include:
●Leukemia and other cancers.
●Some types of anemia.
●Viral infections, such as hepatitis C or HIV.
●Chemotherapy drugs and radiation therapy.
●Heavy alcohol consumption.

3.Increased breakdown of platelets :-

=> Some conditions can cause your body to use up or destroy platelets faster than they’re produced.Leading to a shortage of platelets in your bloodstream.

=> Pregnancy- Usually mild and improves soon after childbirth.
=> Immune thrombocytopenia.
=> Autoimmune diseases, such as Lupus and Rheumatoid arthritis.

ITP :-
If the exact cause of this condition isn’t known, it’s called idiopathic thrombocytopenic purpura. This type more often affects children.

=> Bacteria in the blood.

=> Severe bacterial infections involving the blood (bacteremia) can destroy platelets.
This is a rare condition that occurs when small blood clots suddenly form throughout your body, using up large numbers of platelets.

Hemolytic uremic syndrome :-

This rare disorder causes a sharp drop in platelets,
=> Destruction of red blood cells and impairs in kidney function. Certain medications also can reduce the number of platelets in your blood.
=> Sometimes a drug confuses the immune system and causes it to destroy platelets like.. heparin, quinine, sulfa-containing antibiotics , anticonvulsants.

Complications of Thrombocytopenia….

There are some Dangerous internal bleeding can occur when your platelet count falls below 10,000 platelets per microliter.

Though rare, severe Thrombocytopenia can cause bleeding into the brain, which can be fatal…

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